Diagnostic Bioserve
Science | Medical | Veterinary

Diagnostic Bioserve Ltd has been providing solutions to scientific research, medical & veterinary organisations and professionals from 1996.

We source and distribute innovative products from a variety of internationally recognised manufacturers.

Diagnostic Bioserve
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PO Box 5246, Mount Maunganui 3150, New Zealand.

Phone: +64 7 572 1555

Mobile: +64 21 616 608

Email: Contact us by e-mail

Fax: +64 7 542 2326

Skype: raewyn.jones

DOAC-Stop mini-tablets

About the DOAC-Stop mini-tablets

DOAC-Stop removes all types of Direct Oral Anti-Coagulants (DOACs; dabigatran, apixaban, rivaroxaban, and edoxaban, etc) from test plasmas with minimal effect on underlying blood clotting tests.

Just add one mini-tablet per 1ml test plasma (volume is not critical), mix for 5 minutes and centrifuge down the adsorbent. The resulting plasma is then depleted of DOACs and yields similar APTT, dRVVT , PT(INR) and other results as if DOACs had not been present.

Reversing agents coming into therapeutic use for individual DOACs are not widely available for lab tests. DOAC-Stop is now offered for simplifying the diagnostic problems associated with DOACs.

It absorbs up to an estimated 2,000ng/ml of any DOAC in less than 5 minutes. Unlike therapeutic additives for reversing DOACs it leaves no residual effect. It can be used for checking if DOACs are present in samples giving unexpectedly prolonged clotting test or abnormal chromogenic test results.

There is negligible interference with vitamin K antagonist or heparinoid anticoagulants. Plasmas treated with DOAC-Stop can be used for valid factor assays and in testing for thrombotic risk.

In particular it can prevent false LAC positive results due to DOACs or other agents in testing for lupus anticoagulants. Currently RUO. Patent pending.
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